Soluble CD21 induces activation and differentiation of human monocytes through binding to membrane CD23

Expression Monocytes Induces Immunoregulatory Gene Human Cytomegalovirus Binding to Human

Monocytes Induces Immunoregulatory Gene Human Cytomegalovirus Binding to Human

Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes

rIL-4 (B cell stimulatory factor 1) induces the expression of Fc epsilon R2/CD23 on normal human monocytes (Mo). Fc epsilon R2/CD23 induction was detectable both by flow cytometry using anti-CD23 mAbs as well as soluble IgE, and by the immunoprecipitation with CD23-specific mAb or IgE of a 45-kD band from 125I-lactoperoxidase-labeled Mo. Fc epsilon R2/CD23 was fully expressed after a 24-h incub...

HUMAN RECOMBINANT INTERLEUKIN 4 INDUCES FcER2/CD23 ON NORMAL HUMAN MONOCYTES

Two types of receptors for the Fc portion of human IgE (FccR) have been identified on the surface of human cells. These two types of receptors differ in their affinity for IgE as well as in their cellular distribution and function (1) . Type 1 FcER (FcERI) show high affinity (109/M) for IgE and are detectable on mast cells and basophils (2) . The reaction between allergens and IgE bound to FCER...

Activation of CD21 and CD23 gene expression by Kaposi's sarcoma-associated herpesvirus RTA.

Epstein-Barr virus (EBV) EBNA2 and Kaposi's sarcoma-associated herpesvirus (KSHV) replication and transcription activator (RTA) are recruited to their responsive elements through interaction with a Notch-mediated transcription factor, RBP-Jkappa. In particular, RTA and EBNA2 interactions with RBP-Jkappa are essential for the lytic replication of KSHV and expression of B-cell activation markers ...